Dimethyldioxirane Oxidation of Exocyclic (E,E)-Cinnamylideneketones
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منابع مشابه
Exocyclic Carbons Adjacent to the N6 of Adenine are Targets for Oxidation by the Escherichia coli Adaptive Response Protein AlkB
The DNA and RNA repair protein AlkB removes alkyl groups from nucleic acids by a unique iron- and α-ketoglutarate-dependent oxidation strategy. When alkylated adenines are used as AlkB targets, earlier work suggests that the initial target of oxidation can be the alkyl carbon adjacent to N1. Such may be the case with ethano-adenine (EA), a DNA adduct formed by an important anticancer drug, BCNU...
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ژورنال
عنوان ژورنال: Australian Journal of Chemistry
سال: 2009
ISSN: 0004-9425
DOI: 10.1071/ch08216